The History Of Cialis

The History Of Cialis

Summary: Cialis is a prescription drug for the treatment of erectile dysfunction (ED). Cialis is the brand name of the drug tadalafil. This medication is known technically as a "reversible phosphodiesterase type (PDE) inhibitor". PDE inhibitors increase blood flow to the genitals. More information on how Cialis works is available here. Cialis functions the same way as other PDE inhibitors in the treatment of ED. Viagra, Levitra and Cialis are all PDE inhibitors. As with other ED...

Impotence, Male health, Cialis

Article Body: Cialis is a prescription drug for the treatment of erectile dysfunction (ED). Cialis is the brand name of the drug tadalafil. This medication is known technically as a "reversible phosphodiesterase type (PDE) inhibitor". PDE inhibitors increase blood flow to the genitals. More information on how Cialis works is available here. Cialis functions the same way as other PDE inhibitors in the treatment of ED. Viagra, Levitra and Cialis are all PDE inhibitors. As with other ED drugs, Cialis is only effective during sexual stimulation. The mere act of taking Cialis will not cause an erection in men. Perhaps Cialis can best be defined by comparing and contrasting it with its competitors, Viagra and Levitra:

Cialis is the first joint product of Lilly, an Indiana based pharmaceutical company and ICOS, a biotechnical firm located in Washington state. The search for an effective erectile dysfunction drug began in when ICOS began researching IC, a compound which inhibits the PDE enzyme. The following year ICOSS receives the first patent on IC and in clinical trials start.

Two years later in , ICOS conducts its first study in patients with impotency problems and by , a partnership between Lilly and ICOS is formed. The goal: to commercialize drugs for the treatment of erectile dysfunction.

The following year, , saw the initiation of the Phase III clinical studies on the patented compound.

The newly formed company did not file a new drug application with the Food and Drug Administration until . At this time, the manufacturer names the drug Cialis.

In April of the FDA reviews the application, but declines to approve it. The government agency wants to see more clinical studies, the resolution of some manufacturing issues and the complete labeling for the product.

In May of that year, Lilly ICOS reports that Phase III test results for Cialis are positive. In fact, data demonstrate that Cialis stays in the males system for up to hours, providing a larger window for sexual activity than with Viagra. These findings are presented in Orlando, Florida to the th meeting of the American Urological Association.

Meanwhile, in July , the European Committee Proprietary Medicinal Products recommends the approval of the drug in Europe. Approval comes in November of for European sales, with marketing of the product following in February .

The FDA approves the sales of Cialis in the United States in November .